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Knowledge Center · Diagnostic Tests

Before deciding on any treatment,
I need to understand what your body is telling me.

Weight management is not about a number on the scale, it's about the full metabolic picture. Two people with the same BMI and the same body fat percentage can have completely different underlying conditions: one is a straightforward case of energy imbalance; another has PCOS, hypothyroidism, or elevated cortisol working in the background. Without the right assessment, treatment decisions are guesswork.

Dr. Kong-Han Ser

When patients come in and ask "what tests do I need?", I turn the question around: what do you want to know? Testing isn't a set menu, more isn't better. Every test should have a specific question it's designed to answer: "Is there a hidden cause behind this obesity?" or "Is it safe for this person to undergo this treatment?" Without a clear question, you just end up with a pile of numbers.

Why assess?

Why does obesity treatment require diagnostic assessment?

Most people expect obesity-related testing to mean a blood draw, a body fat scan, and a BMI calculation. Those are done, but they're only the beginning. In bariatric medicine, assessment serves two distinct purposes. Missing either one compromises the quality of the treatment decision.

Purpose one: identify whether there's a hidden cause behind the obesity. Most cases involve a combination of caloric intake and lifestyle factors, but not all. Polycystic ovary syndrome (PCOS), hypothyroidism, Cushing's syndrome, and pituitary conditions can all cause weight to accumulate in a way that's distinct from typical obesity, and requires a different treatment direction. Without this layer of assessment, a patient can spend years being managed as "general obesity" when the underlying issue is hormonal and requires endocrine specialist input first.

Purpose two: assess whether the patient can safely tolerate the proposed treatment. Whether the treatment is GLP-1 medication, endoscopic sleeve gastroplasty, or metabolic surgery, each has its own indications and contraindications. Cardiopulmonary capacity, liver and kidney function, nutritional reserves, and anesthesia risk all need to be known before treatment begins.

"Testing isn't a menu to order from, it's what makes treatment decisions precise. One unnecessary test is waste. One missing test is risk."

Find hidden causes behind the obesity
Assess safety and suitability for treatment
Every test should answer a specific clinical question
Dr. Kong-Han Ser

I've seen many patients arrive with thick folders of test results from other clinics, asking me "do these mean I should have surgery?" After reviewing them, I've said more than once: you've done a lot of tests, but you're missing several of the ones that would actually change the clinical decision, and a few of these expensive advanced scans are completely irrelevant to your situation. The value of testing is never in the volume. It's in whether the right questions are being answered.

Three categories

The three categories of obesity-related assessment

Blood work, endocrine evaluation, and abdominal imaging, each answers a different layer of clinical questions.

Note: the following explains the purpose and scope of each category. Which specific tests are ordered, and in what sequence, is determined by Dr. Ser based on your individual clinical picture.

Blood work

The most fundamental tool, and the one that most directly reflects what metabolic state the body is currently in.

This is not just cholesterol and blood sugar. The more important signals are insulin resistance, chronic inflammation markers, and baseline liver and kidney function. These numbers directly affect the answers to "should we intervene?", "how?", and "at what intensity?"

Typically includes:

  • Fasting glucose, HbA1c, fasting insulin, HOMA-IR (insulin resistance index)
  • Lipid panel: total cholesterol, triglycerides, LDL, HDL
  • Liver function, kidney function, uric acid
  • Chronic inflammation markers (e.g. hs-CRP)
  • When indicated: nutritional baseline, iron, Vitamin D, B12

Endocrine evaluation

Not everyone needs this layer, but when it's indicated and missed, the clinical consequence is significant.

Dr. Ser assesses whether deeper endocrine evaluation is warranted based on your symptoms, fat distribution pattern, menstrual history, comorbidities, and family history. Obesity caused by endocrine dysregulation requires a different treatment direction from typical obesity. PCOS requires simultaneous management of insulin resistance and androgens; hypothyroidism needs thyroid hormone restoration before weight loss can be addressed.

May be assessed depending on individual presentation:

  • Cortisol (assessing stress hormone and Cushing's syndrome)
  • Female hormones: FSH, LH, E2, Progesterone, Testosterone, AMH (complete PCOS and ovarian function panel)
  • Male hormones: FSH, LH, E2, Testosterone, SHBG (including free testosterone)
  • Prolactin
  • Thyroid function: TSH, T3, T4 (added based on clinical presentation)

Abdominal imaging

Abdominal ultrasound is the primary tool, examining the liver and biliary system.

Obesity and fatty liver are closely linked. Early-stage fatty liver has no symptoms, blood tests can only indicate liver enzyme elevation, not what the liver actually looks like. Gallstone prevalence is also elevated in patients with obesity, particularly after rapid weight loss. Pre-surgical imaging assessment affects both the surgical approach and timing.

Primarily assesses:

  • Degree of hepatic steatosis (mild, moderate, severe)
  • Gallstones, gallbladder polyps
  • When indicated: kidneys, pancreas, spleen
  • For deeper assessment: hepatic fibrosis stage (FibroScan or equivalent)
Dr. Kong-Han Ser

On endocrine evaluation: I assess this not because I'm trying to do an endocrinologist's work, but because obesity and endocrine dysfunction are often two aspects of the same underlying condition. Looking at them separately misses the point. If assessment shows that your situation needs to be handled by endocrinology first, I'll refer you, not because I'm unwilling to operate, but because that's the correct clinical judgment for your specific case.

Different stages, different priorities

The three categories above apply to the initial evaluation phase, establishing baseline and identifying what needs to be addressed first. Once a patient enters the post-surgical phase, the focus shifts entirely.

Initial evaluation

Question being answered: Are there hidden causes behind this obesity? What treatment direction is appropriate?

Primary tests: The three categories above, blood work, endocrine evaluation, abdominal imaging. Goal: establish a baseline and identify conditions that need to be addressed before treatment begins.

Post-surgical follow-up

Question being answered: Is nutritional status keeping up? Are the body's reserves holding?

Primary tests: Comprehensive nutritional monitoring panel, tracked at regular intervals. Surgery alters how the body absorbs nutrients, this layer of monitoring is non-negotiable and continues for many years.

Post-surgical nutritional monitoring, standard panel (12+ items)

· Vitamin A
· Vitamin D (25-OH)
· Vitamin E
· Vitamin B12
· Vitamin C
· Folate
· Iron / Ferritin
· Zinc
· Calcium (+ iPTH)
· Magnesium
· Potassium
· Albumin

These are not checked once before surgery and forgotten. They are tracked at regular intervals post-operatively. Bariatric surgery doesn't only change body weight, it changes the relationship between your body and nutrients. This monitoring continues for years.

Before treatment

What else is assessed before treatment: and why

When treatment enters the level of GLP-1 medication, endoscopic sleeve gastroplasty, or metabolic surgery, assessment takes on a second dimension beyond "what's behind the obesity." The question becomes: "can this person safely tolerate this treatment?"

This layer evaluates: cardiopulmonary capacity, anesthetic risk, nutritional reserves, and psychological readiness. Each form of treatment disturbs the body in some way, medications carry side effects to be managed, surgery involves anesthesia and a recovery period, and the post-surgical dietary structure changes significantly. If the body is already in a state of nutritional deficiency, anemia, or borderline cardiac or pulmonary function before treatment begins, the risk of the treatment itself is amplified.

Psychological readiness is also part of this assessment. Metabolic surgery is not "lie down, wake up thinner." It requires long-term follow-up, dietary adjustment, and navigating the psychological experience of rapid body change. If the mental groundwork isn't in place, treatment outcomes are diminished and complication risk rises.

Specific assessment items, test sequences, and timing are arranged by the team on an individual basis during your consultation. For a more detailed look at the surgical process, see the Surgery Q&A page.

"Pre-treatment assessment isn't a hurdle. It's protection. I want you to be living better after treatment, not just lighter."

Cardiopulmonary capacity
Anesthetic risk assessment
Nutritional reserves
Psychological readiness
Common misconceptions

Three tests I'll tell you not to bother with

Some tests are heavily marketed in the weight loss industry, packaged to look scientific, but with limited clinical utility. These are the ones I'll tell patients directly: you don't need this.

Misconception 01

Weight loss genetic testing: I can order it, but you need a specific reason

You may have seen "weight loss genetic testing" offered at other clinics, claiming to analyze which diet suits you, which exercise, where you tend to accumulate fat. My position is direct: I can order this test, but you need a concrete reason to do it.

International obesity treatment guidelines (including those from the American, European, and Asian bariatric surgery societies) do not list genetic testing as a basis for pre-surgical decision-making. The treatment direction for most common obesity presentations is established through history, lifestyle assessment, blood work, and targeted endocrine or imaging evaluation when indicated. A genetic report showing "tendency to gain weight" or "tendency to accumulate abdominal fat" has limited weight in clinical decision-making, treatment strategy is determined by your BMI, comorbidities, what approaches have been tried, and body system assessment. Not a single genotype.

That said, clinical decisions don't only come down to medical necessity. If you've had long-standing uncertainty about your metabolic constitution, and doing the test would give you confidence and motivation to commit to treatment, then it has value for you. In that case, I'm willing to arrange it.

I want your choices to be driven by "what information do I want to get?", not by "will I miss something if I don't do this?" Testing that doesn't serve a clear purpose is not worth doing.
Misconception 02

"Premium" advanced imaging isn't necessarily better

CT, MRI, PET-CT, these are powerful tools for the specific clinical problems they're designed to address. Used as a "full-body sweep to look for causes of obesity," they're generally over-investigation.

Most of what bariatric medicine needs to answer can be addressed through blood work, abdominal ultrasound, and targeted endocrine testing where indicated. If initial assessment points toward a need for deeper imaging, that should absolutely be done, but "let's do it first and see" doesn't improve treatment precision. It redirects time and cost toward results that have no clinical bearing on your case.

Misconception 03

"More reports means better decisions" is wrong

Some patients arrive with thick stacks of results from multiple clinics, assuming that more data makes the picture clearer. Usually, the opposite is true: data without a clinical question as its anchor tends to mislead rather than inform.

A glucose result from a non-fasting draw, a female hormone panel taken at the wrong point in the menstrual cycle, an inflammatory marker done during an acute illness, these numbers, stripped of their clinical context, can obscure what actually deserves attention. The value of a test is always tied to the question it was designed to answer.

Dr. Kong-Han Ser

I write this because I've seen too many patients spend money outside, do a series of impressive-looking tests, and end up receiving treatment recommendations no different from what a general nutritionist would have given them. I'd rather you keep that money for tests that genuinely affect the clinical judgment, and for treatment that creates lasting improvement.

FAQ

Questions from the clinic

Practical questions about costs, existing reports, fasting, process, and more.

Q1I can't travel to Taiwan in person yet. What tests and reports should I prepare before a remote consultation?

A meaningful remote consultation requires an actual clinical picture, not just a weight and BMI. The more complete the information you bring, the more concrete the assessment can be. Here's what to prepare:

Recommended preparation for remote consultation

1

Fasting blood work, done within the last 3 months

The most important: fasting glucose, HbA1c, fasting insulin, HOMA-IR, lipid panel (total cholesterol, triglycerides, LDL, HDL), liver function (ALT, AST, GGT), kidney function, uric acid. If available: hs-CRP, Vitamin D, B12, ferritin/iron.

2

Abdominal ultrasound report, within the last 1 year

Liver, gallbladder, kidneys. Most health check ultrasounds cover this. Bring the original report, "grade 2 fatty liver" is more useful than a verbal summary.

3

Current height, weight, waist circumference

Measured on the same day as the consultation if possible. A recent photo (front and side) is also helpful if you're comfortable sharing one.

4

Current medications and supplements, full list

Include dosages and how long you've been taking them. This affects which additional tests may be needed and which are already partially answered.

5

Endocrine reports, if you have them

Thyroid function (TSH, T3/T4), sex hormones, PCOS-related panels. If you've been diagnosed with a hormonal condition, bring the records and current treatment notes.

6

Weight history and prior approaches

Approximate weight at key life stages. What weight loss methods you've tried, for how long, and what happened. This context significantly changes the clinical picture.

7

Relevant comorbidities and family history

Diabetes, hypertension, dyslipidemia, sleep apnea, PCOS, fatty liver, gout, any condition you've been diagnosed with. Family history of diabetes, cardiovascular disease, or obesity-related conditions.

If you don't have some of these, bring what you have. The consultation will help identify what gaps need to be filled before treatment planning can proceed, either with tests arranged locally or after arriving in Taiwan.

Q2Can I use reports from another hospital? How recent do they need to be?

Yes, please bring them. Here's how they're evaluated:

  • Within 3 months: Blood work is generally usable, unless your condition has changed significantly (recent medication change, major weight shift).
  • 3–6 months: Used as background reference; key items may be re-tested.
  • Over 6 months: Usually re-tested, as metabolic markers shift with weight, medication, and lifestyle changes.

Abdominal imaging (ultrasound, other imaging reports): anatomical findings are more stable, within 1 year is generally usable, unless there's a specific new clinical question.

Bringing something is always better than not bringing it. Even older results establish your historical trajectory.

Q3Do I need to fast before blood work? How long?

Yes, fasting is required. The standard is 8–10 hours without eating before the draw (water is fine).

The simplest approach: finish dinner the evening before, drink only water after that, and draw blood the following morning.

The reason: blood glucose, triglycerides, and fasting insulin are all affected by food intake. Without fasting, these results are uninterpretable, the draw is wasted.

Special situations:

  • If you're on diabetes, blood pressure, or cholesterol medications → take them as normal; don't skip them for the blood draw.
  • For a morning draw: ideally finish dinner before 10pm the night before.
Q4How long does the full assessment take? How many visits?

The ideal process involves 2 visits:

First visit (~30 minutes): Consultation + blood draw + imaging referral. If you fast the night before, the blood draw can happen on the same day. If not, a second fasting visit is arranged.

Imaging (separately scheduled): Abdominal ultrasound, and FibroScan if indicated, through the hospital imaging department.

Second visit (~30 minutes, 1–2 weeks after blood work): Full report review and treatment direction discussion. All results are reviewed together, current status of your body systems, what needs to be addressed first, and what the treatment pathway looks like.

Overall timeline: approximately 2–3 weeks, across 2–3 visits. If further endocrine evaluation is needed, one additional blood draw is added.

Q5I'm male / my cycles are regular / I have no PCOS symptoms, do I still need endocrine testing?

Not necessarily, it's determined by clinical judgment. Endocrine testing is not a standard add-on for everyone. The decision is based on:

  • Fat distribution pattern: pronounced central obesity, moon face, buffalo hump → consider cortisol
  • Symptom signals: heat/cold intolerance, persistent fatigue, skin changes → consider thyroid function
  • Medical and family history
  • Initial blood work results: if fasting insulin or HbA1c are abnormal, further endocrine items may follow

Men can also need this: obesity-related hypogonadism (low testosterone) is not uncommon in men and may be assessed.

If your basic blood work is unremarkable, fat distribution is uncomplicated, and there are no specific symptoms, the endocrine panel may not be necessary. Avoiding unnecessary testing is also part of clinical judgment.

Q6I've already been diagnosed with PCOS / hypothyroidism elsewhere. Do I need to re-test?

Not necessarily a full panel re-run, but a directional update will be done:

  • PCOS: If previously diagnosed, the current treatment status, menstrual pattern, and weight trend are reviewed. A retest of insulin resistance markers and androgens (which change with treatment) may be recommended.
  • Hypothyroidism: If on regular thyroid hormone replacement, bring a recent TSH result (within 3–6 months). If none available, retesting once is recommended as a baseline.
  • Cushing's syndrome or other endocrine conditions: Bring complete records and medication history. Coordination with the treating endocrinologist or specialist avoids unnecessary duplication of advanced tests.

Core principle: Don't repeat tests that have no additional meaning. But don't assume a past result is current, key markers get updated when clinically indicated.

Q7I won't understand my report. Can I send it to you in advance?

Yes, but the complete interpretation is done in the consultation.

You can send reports in advance via WhatsApp or email to the case manager, who can flag any particularly notable values and advise on next steps. But a complete clinical interpretation needs to happen in consultation, because reading a report isn't just "this number is outside range." It requires your body composition, symptoms, medication history, and family history together. That context can't be properly assembled over a message.

If you're anxious after receiving results and want a preliminary read, send them in. But the clinical judgment is done in the consultation, not over chat.

Q8I've already done a weight loss genetic test. Can I bring it?

Yes, bring it, I'll look at it, but it won't be the primary basis for treatment decisions.

My position on genetic testing is stated in the misconceptions section above: it has a place, but it isn't a required pre-treatment assessment item.

If you've already done it, I'll:

  1. Cross-reference it with blood work, endocrine, and imaging findings
  2. Look for any clinically meaningful signals (some insulin resistance-related gene variants may affect medication selection)
  3. But I won't change the treatment strategy because the report says "tendency to gain weight." Treatment strategy is still determined by BMI, InBody composition, comorbidities, and what has previously been tried.

In short: worth bringing, but don't expect it to significantly change direction.

Q9My health check included an abdominal ultrasound. Can I use that, or does it need to be redone?

Within 1 year, most health check ultrasounds can be used.

Health check ultrasounds typically cover liver, gallbladder, pancreas, spleen, and kidneys. Anatomical findings (fatty liver grade, gallstones, cysts) don't change quickly, within 1 year is generally acceptable.

Situations where a re-scan may be recommended:

  • Significant weight change in the past year (especially substantial gain) → fatty liver grade may have changed
  • Report only states "mild/moderate/severe fatty liver" without a FibroScan → FibroScan may be needed to quantify hepatic fibrosis
  • Report notes any item flagged for further follow-up → re-evaluation is advisable

Please bring the complete report. It will be reviewed item by item, and you'll be told what's usable and what needs to be supplemented.

Q10My tests show fatty liver / pre-diabetes / PCOS. Does that mean I need surgery?

No. The purpose of assessment is to give you an accurate picture of your body's current state, not to funnel everyone into a surgical pathway.

Discovering a metabolic condition opens up a range of treatment options, not a single one:

  • Lifestyle intervention: dietary adjustment, exercise, behavioral change, always the first consideration where feasible
  • GLP-1 medication: effective for metabolic conditions at appropriate BMI ranges; well-supported by evidence
  • Endoscopic procedures: non-surgical options for certain situations
  • Metabolic surgery: indicated when other approaches have been genuinely tried and haven't achieved sufficient improvement, particularly where comorbidities are significant

The specific path depends on the full clinical picture, your BMI, comorbidity severity, what you've tried before, and your own goals and preferences. That's the conversation we have at the second consultation, after all results are in.

Ready to start?

Bring what you have. We'll work out what else is needed.

Whether you're coming in person or beginning with a remote consultation, the first step is the same, a clear look at where things actually stand.

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